General Information

  • ID:  hor000459
  • Uniprot ID:  E9G0B6
  • Protein name:  Allatostatin A6
  • Gene name:  NA
  • Organism:  Daphnia pulex (Water flea)
  • Family:  Allatostatin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Daphnia (genus), Daphniidae (family), Anomopoda (infraorder), Cladocera (suborder), Diplostraca (order), Phyllopoda (subclass), Branchiopoda (class), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  GO:0005184 neuropeptide hormone activity
  • GO BP:  GO:0007165 signal transduction
  • GO CC:  NA

Sequence Information

  • Sequence:  LPVYNFGL
  • Length:  8(258-265)
  • Propeptide:  MLFLSTALFLLVALLQSSQCTDVNNDSSVIEAVGAGGGDSQAKAESLASAEDKLSALTADGMATRARYFKSFGGNPTGDPNLNIYSFGLGKRTSRSYSINPYSFGLGKRGGNAKSYPQQIPYSFGLGKRNPTKYNFGLGKRPDRFGFGLGKRNLKDDDLDQWLNDEEYSQFDDTEEEIEGREDDSQEIMDVNKRSQMAAGQQQQQQQQAFFPSHLQSAFYGGPFMSNLARANTHALGKSRTFNQQAATHDLPNLG
  • Signal peptide:  MLFLSTALFLLVALLQSSQC
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-E9G0B6-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor000459_AF2.pdbhor000459_ESM.pdb

Physical Information

Mass: 104713 Formula: C46H67N9O11
Absent amino acids: ACDEHIKMQRSTW Common amino acids: L
pI: 6.09 Basic residues: 0
Polar residues: 3 Hydrophobic residues: 4
Hydrophobicity: 97.5 Boman Index: 1102
Half-Life: 5.5 hour Half-Life Yeast: 3 min
Half-Life E.Coli: 2 min Aliphatic Index 133.75
Instability Index: 2868.75 Extinction Coefficient cystines: 1490
Absorbance 280nm: 212.86

Literature

  • PubMed ID:  21830762
  • Title:  Genomics, Transcriptomics, and Peptidomics of Daphnia Pulex Neuropeptides and Protein Hormones